Innovation

Systems and Methods for Endoscopic Vertebral Fusion (BIDMC 1106)

Beth Israel Deaconess Medical Center
posted on 01/12/2012

A novel therapy to prevent or repair the damaged GBM by administering stem cells which then become kidney epithelial cells and provide normal GBM components, such as collagen.

Certain kidney diseases result from defects in the glomerular basement membranes (GBM), crucial to proper kidney function. Alport’s Syndrome, for example, is an inherited disease of kidney inflammation (nephritis) resulting from a mutation in collagen, a key GBM component. Treatment options for diseases with impaired GBM are dialysis or renal transplantation. While these treatments may increase a patient’s survival, quality of life remains poor.


Innovation Details
 

File Number: 805 

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Investigator(s)
Dr. Kevin McGuire

Contact
Stanley, Mah C


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February 11, 2009

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