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Methods to treat symptoms of aging
Sanford-Burnham Medical Research Institute
posted on 06/04/2010
Biologicals
Aging - Diabetes - Metabolic Diseases
- Stem Cell Biology -
Therapeutics
The
current invention provides methods of modulating the insulin/IGF pathway
to treat symptoms related to
aging.
Features
·
Reduces symptoms of
aging
Background
Glucose
and lipid homeostasis is maintained in higher organisms through the
insulin/IGF pathway. Substances that decrease insulin signaling and thus
inhibit stem cell aging are useful for promoting tissue healing, repair,
and regeneration, slowing the aging of tissues and organs, as anti-cancer
therapeutics, and as anti-obesity and anti-diabetes therapeutics. The
current invention provides methods of modulating the insulin pathway to
treat symptoms of aging.
Lead
Inventor
Sean Oldham, Ph.D.
Selected References
Luong, N. et al. Cell Metab. 2006 Aug;4(2):133-42.
Patent
Information
Full title: Compositions and methods for treatment of symptoms of aging
U.S. Patent/Application #: 61/317,177
Priority date: 3-24-2010
Foreign filing: tbd
Sanford-Burnham ID: 07-042
Status
Available for license
File Number: 07-042/OLDHAM*
This innovation currently is not available for online licensing. Please contact Glenn Dourado, M. Sc., MBA at Sanford-Burnham Medical Research Institute for more information.
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