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Potential anticonvulsant treatment for the epilepsy seizure
Caritas St. Elizabeth's Medical Center
posted on 02/13/2009
Description: Pyramidal cells are large, pyramid shaped excitatory neurons found in the hippocampus and cerebral cortex. Dr. Wang has identified a novel way of inhibiting the activity at pyramidal gap junctions. Experimental results suggest that this inhibitor can be used as a potential anticonvulsant agent for pathological hypersynchrongy, such as epilepsy. Pyramidal gap junctions are quickly and reversibly inhibited by beta-amyloid as an anticonvulsant. It is believed that this approach will produce much fewer side effects that other gap inhibitors have produced.
File Number: CSEMC-016
Other Information:
Investigator(s)
Yun Wang
Contact
Todd Keiller, fax 508/497-0733
This innovation currently is not available for online licensing. Please contact Abi Barrow at Caritas St. Elizabeth's Medical Center for more information.
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