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Methods for Eliciting an Immune Response to Bacterial Infections
Duquesne University of the Holy Spirit
posted on 03/01/2009
Methods for Eliciting an Immune Response to Bacterial Infections
Suggested Uses
Vaccines and Diagnostics
Advantages
This method allows for vaccine preparation which does not require the cumbersome isolation, purification, and treatment involved with current methods. This process avoids the dangers of growing and handling the pathogenic organisms and the need for special containment facilities.
Detailed Description
A Duquesne University researcher has developed a method to produce target vaccines against various gram negative bacteria. The method involves attaching O-antigens of different species to the pilin of a gram negative bacterium such as Pseudomonas aeruginosa. The O-antigen repeating unit attached to the pilin evokes a stronger and longer lasting immune response. In addition to being used as a vaccine, this method can be used as a diagnostic tool to test for the presence of antibodies.
File Number: 7,132,101
Web site: http://www.research.duq.edu
Disease: Infectious Diseases
| Patent Number(s): | 7132101 |
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This innovation currently is not available for online licensing. Please contact Alan Seadler at Duquesne University of the Holy Spirit for more information.
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