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Functionally Inhibitory JAML Monoclonal Antibodies
Emory University
posted on 01/18/2012
Applications
- Flow Cytometry
- Immunoprecipitation
- Functional Assays
Specificity
Human
Subtype
Mouse Monoclonal
Immunogen
Recombinant human JAML
Technical Summary
Junctional adhesion molecules (JAMs) are a family of glycoproteins important in the control of vascular permeability and leukocyte transmigration across endothelial-cell surfaces. JAMs play a vital role in epithelial inflammation by regulating leukocyte transmigration and barrier function. Emory researchers have created several mAbs that bind differently to JAML with partial to complete inhibition of JAML ligands.
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This innovation currently is not available for online licensing. Please contact Panya Taysavang at Emory University for more information.
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Principal Investigator:
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Charles Parkos
Innovations (7) Publications (6) |
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Co-Investigators:
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Dominique Weber
Innovations (1) |
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Case Manager:
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Panya Taysavang
Innovations (74) |
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