Rare diseases

"A rare disease, sometimes known as an orphan disease, is any disease that is not common...No single cutoff number has been agreed upon for which a disease is considered rare. A disease may be considered rare in one part of the world, or in a particular group of people, but still be common in another." - Wikipedia

Innovation represented on the iBridge Network targets diseases such as Cystic Fibrosis, Huntington disease, mesothelioma and genes such as BRCA1, BRCA2, and FAP.

The Latest Innovations

Fox Chase Cancer Center 16 DEC 11	Anti-murine Fibroblast Activation Protein (FAP) Polyclonal Antisera Dr. Cheng and colleagues of Fox Chase Cancer Center have developed rabbit polyclonal antisera against recombinant murine FAP-ECD protein. These antisera can detect murine FAP in vitro and in vivo and have been used to detect FAP on paraffin embedded xenografts
University of Utah 31 MAR 11	Colon Tumor Specific Binding Peptides Invention Summary: A short, cyclic peptide selectively binds and is internalized into colon cancer cells. It discriminates colon tissue from normal tissue and other cancer types. This invention targets HT29 cells. The APC gene is mutated in HT29 cells and 85% of colon cancers including all ...
University of Utah 31 MAR 11	The APC gene, for Detection and Diagnosis of Inherited and Sporadic Colorectal Cancer Invention Summary: The adenomatous polyposis coli (APC) gene is a tumor suppressor gene which is altered in many colon cancers. Germline mutations of APC are the cause of familial adenomatous polyposis (FAP), an inherited syndrome which leads to the growth of hundreds of colon polyps and a ...
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