Method for and Creation of High Mechanical Performance Biocompatible Interpenetrating Network (IPN) Hydrogels for Tissue Engineering

University of Kansas
posted on 08/07/2009

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Description: KU researchers have developed a novel synthesis procedure to create hydrogels with mechanical properties desirable for musculoskeletal tissue engineering, with moduli (stiffnesses) comparable to cartilage and failure properties (strength and toughness) far beyond hydrogels currently used in tissue engineering. KU has also shown that the synthesis and encapsulation process is conducive to cell viability. The significance of this discovery is that by creating these hydrogels of high toughness, one can overcome a major limitation of current hydrogel scaffolds, as high toughness is crucial to constructs for them to withstand fracture in demanding environments such as a human knee or hip. Patent: Pending Confidential Disclosure Agreement (CDA): KU is willing to enter into a CDA for the purpose of negotiating a License Agreement. If you are interested in learning details of this invention, please contact: Aswini K. Betha, Ph.D. (abetha@ku.edu Ph: 913-588-5713)