Treatment planning software for pencil-beam proton radiotherapy

Massachusetts General Hospital
posted on 05/27/2011

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Technology: The inventors have developed software systems for treatment planning and validation of proton radiotherapy with pencil-beam scanning. The software systems provides a complete set of subsystems for: - Dose computations, including primary and secondary interactions and the opportunity to use apertures, range-shifters and range-compensators - True robust multi-criteria optimization algorithms that allow real-time evaluation of trade-off analysis of competing treatment objectives - Rigorous database management of complex, large and multi-threaded data instances and computations - Validation of individual treatment fields through redundant dose computations in phantom and comparison against measurement - Track optimization and validation against delivery equipment specific features The technologies were developed and validated in-toto for clinical deployment and use at the Massachusetts General Hospital. The systems, in whole and in parts, provide the necessary framework and development tools for the clinical use of pencil-beam scanning. Applications: - Proton Radiotherapy (Pencil Beam Scanning) Advantages: - Interactive user interface to allow comparison of the treatment plans - Desired trade-off of benefit versus potential tissue damage - Data management for treatment planning - Quality assurance and treatment delivery optimization of a pencil-beam proton field - Efficient development and deployment environment for radiotherapy applications