Evaluating Intelligibility of Speech Reproduction

Massachusetts Eye and Ear Infirmary
posted on 01/07/2009

This complex software program allows the user to facilitate the analysis of hearing loss and the fitting of hearing aid devices to best match the particular deficiencies (articulation index, intelligibility of speech and transmission) of the hearing impaired person to the best device suited to meet those particular needs and to help predict the extent to which individuals will likely benefit from having hearing aids. Could be tailored for remote applications with proper audiological support.

Advantages

High selectivity,Low side toxicity,Derivative of naturally occurring peptide,Proven antimicrobial activity of natural peptide

Innovation Details

Detailed Description

The cathelicidin, antimicrobial peptide found in mammals, LL-37 is the only known human cathelicidin to confer protection from bacterial infection. Despite the high bacterial toxicity, the clinical application was very limited due to high number of serious side effects. Researchers at the University of Nebraska Medical Center successfully have modified LL-37 to produce novel compound with highly selective antimicrobial activity and reduced side toxicity.

File Number: 9

Web site: http://www.meei.harvard.edu

Other Information:

Investigator(s)
Zezhang Aaron; Hou Thornton

Contact
Lisa Putukian, 617-573-4404

IP Protection

License Online

This innovation currently is not available for online licensing. Please contact Abi Barrow at Massachusetts Eye and Ear Infirmary for more information.

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