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Antibody against P70 Surface Antigen of M. hyorhinis (clone AB3P)
University of Missouri System: University of Missouri-Columbia
posted on 07/22/2011
Mycoplasma hyorhinis is the primary agent of pig pneumonia found world-wide and results in large economic losses. MU inventors have developed a mouse monoclonal antibody that works with a variety of applications to detect M. hyorhinis such as the testing, diagnosis and monitoring of infected animals as well as possible vaccine development. It is an ideal product for potential commercial utilization.
The respiratory infection caused by M. hyorhinis may be chronic, have high morbidity and low mortality rates, and cause significant economic losses. In addition, mycoplasmas can be human pathogens and Mycoplasma hyorhinis has been linked to gastric cancer and other gastric diseases.
The current invention developed by researchers at University of Missouri is a mouse monoclonal antibody against the P70 surface protein antigen of Mycoplasma hyorhinis.
Suggested Uses
- Testing, diagnosis and monitoring of infected animals
- Development of a vaccine against M. hyorhinis
- Monitoring of cell lines for contamination by M. hyorhinis
Advantages
- Hybridoma cell line available
- IgG1 k isotype allows for easy affinity purification
- P70 is constitutively expressed on M. hyorhinis
- The antibody does not cross-react with other mycoplasma species
- Works with ELISA, Western, immunohistochemistry, and more
Detailed Description
STATE OF DEVELOPMENT
Ready to use
LICENSING POTENTIAL
University seeks licensee with potential to commercialize
PATENT STATUS
No patent application on file
TECHNOLOGY INNOVATOR
Kim S. Wise
File Number: 11UMC027
Disease: Respiratory and Pulmonary System
Other Information:
TECHNOLOGY MANAGER CONTACT
Harriet F. Francis, MS, JD
Senior Licensing Associate
Email: francish@missouri.edu
Phone: 573-884-0374
This innovation currently is not available for online licensing.
Please contact Harriet Francis at University of Missouri Office of Technology and Industry Relations for more information.
This innovation currently is not available for online licensing. Please contact Harriet Francis at University of Missouri System: University of Missouri-Columbia for more information.
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