Innovations (11):

• Discovery of Aminoquinolines as a New Class of Potent Inhibitors of Heat Shock Protein 90 (Hsp90)
• Selective Inhibitors For Cyclin-Dependent Kinases
• Triptolide Analogs as Anti-Inflammatory Agents
• Methods for the Esterification of Alcohols and Compounds Useful Therefor
• Method of Altering Sphingolipid Metabolism and Detecting Fumonsin Ingestion and Contamination
• 15-Lipoxygenase Polycationic Oligomers
• Curcumin Analogs with Antitumor and Antiangiogenic Properties
• A Novel Category of Bioactive Diiminopiperazines
• Synthetic Analogues of Progesterone
• Sythesis of Enigmol and its Analogues

Selected Publications (7):

• 2010. XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH. Urology 75(4):755-61.
• 2010. Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases. Bioorganic & medicinal chemistry letters 20(3):841-3.
• 2009. Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism. Bioorganic & medicinal chemistry letters 19(23):6627-31.
• 2009. Cancer and virus leads by HTS, chemical design and SEA data mining. Current topics in medicinal chemistry 9(13):1159-71.
• 2009. Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury. Journal of medicinal chemistry 52(19):6012-23.
• 2009. Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors. Bioorganic & medicinal chemistry 17(17):6463-80.
• 2009. Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting. Nucleic acids research 37(13):4472-81.