Innovations (8):

• Amino Acid Enantiomers for Tumor Imaging
• Novel PET Imaging Agents for the Diagnosis of Prostate and Other Cancers
• Alzheimer's Disease Imaging Agents
• 4-Haloalkenyltropanes for Imaging the Serotonin Transporter
• Radio-Halogenated Pyrroliosoquinolines for Imaging Serotonin Transporters
• Radio-Halogenated Flurobutenyl Tropanes for Imaging Dopamine Transporters
• Radio-Halogenated Nortropanes for Imaging Serotonin Transporters
• CRF-1 Receptor Antagonists for PET Imaging or as Potential Therapeutics

Selected Publications (7):

• 2010. Synthesis and biological evaluation of anti-1-amino-2-[18F]fluoro-cyclobutyl-1-carboxylic acid (anti-2-[18F]FACBC) in rat 9L gliosarcoma. Bioorganic & medicinal chemistry letters 20(7):2140-3.
• 2010. Synthesis, radiolabeling, and biological evaluation of (R)- and (S)-2-amino-3-[(18)F]fluoro-2-methylpropanoic acid (FAMP) and (R)- and (S)-3-[(18)F]fluoro-2-methyl-2-N-(methylamino)propanoic acid (NMeFAMP) as potential PET radioligands for imaging brain tumors. Journal of medicinal chemistry 53(2):876-86.
• 2010. Cortical activation during cocaine use and extinction in rhesus monkeys. Psychopharmacology 208(2):191-9.
• Initial experience with the radiotracer anti-1-amino-3-[18F]Fluorocyclobutane-1-carboxylic acid (anti-[ 18F]FACBC) with PET in renal carcinoma. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 11(6):434-8.
• 2009. Stereoselective synthesis and biological evaluation of syn-1-amino-3-[18F]fluorocyclobutyl-1-carboxylic acid as a potential positron emission tomography brain tumor imaging agent. Bioorganic & medicinal chemistry 17(5):1982-90.
• 2009. Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine. PET clinics 4(1):101-128.
• 2009. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter. Journal of medicinal chemistry 52(1):62-73.