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Use of Channel Blockers in the Treatment of Epilepsy
University of Rochester
posted on 07/01/2009
Use of Channel Blockers in the Treatment of Epilepsy
Suggested Uses
A method of treatment of epileptic seizures by blocking the release of glutamate from asctrocytes.
Advantages
This method is more efficient and should have fewer side effects than current epilepsy therapies. This technology has demonstrated that regulated astrocytic glutamate release may underlie the development of epilepsy. Further, in vitro and in vivo models have been developed to aid in the development and screening of therapeutic drug candidates.
Detailed Description
A method of treatment of epileptic seizures by blocking the release of glutamate from asctrocytes.
This method is more efficient and should have fewer side effects than current epilepsy therapies. This technology has demonstrated that regulated astrocytic glutamate release may underlie the development of epilepsy. Further, in vitro and in vivo models have been developed to aid in the development and screening of therapeutic drug candidates.
File Number: 6-1366
Other Information:
- Refer to: Case # 6-1366
- Lead Innovator: Dr. Maiken Nedergaard
- Case Manager: Harl Tolbert, MS, MBA
- harl_tolbert@urmc.rochester.edu
This innovation currently is not available for online licensing. Please contact Harl Tolbert at University of Rochester for more information.
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