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Application of Ndy-1, a novel nuclear oncoprotein, for the immortalization of hematopoietic stem cells
Tufts Medical Center
posted on 02/10/2009
Tufts Medical Center Categories:
diseases:cancer
diseases:dermatologic
therapeutic:gene therapy
Additional Keywords:
senescence, leukemia, lymphoma, immortalization
Invention Summary
Available from Tufts Medical Center
Compositions and methods for immortalizing, or for inhibiting growth of cells by targeting the Rb and p53 pathways with the protein encoded by the Ndy1 gene are provided, and the protein presents a new target for identifying anti-cancer compounds.
File Number: TMC-352
Other Information:
Investigator(s)
Philip Tsichlis
Contact
John Cosmopoulos
617-636-0366
john.cosmopoulos@tufts.edu, John Cosmopoulos
617-636-0366
john.cosmopoulos@tufts.edu
This innovation currently is not available for online licensing. Please contact the case manager at Tufts Medical Center for more information.
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