Novel and unique ocular drug delivery technology (POD) for enhanced delivery of drugs to ocular tissues and cells

Tufts University
posted on 01/07/2009

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Tufts University Categories:
diseases:ophthamological

Additional Keywords:
(none specified)

Invention Summary

Researchers at Tufts University have identified a novel and unique peptide known as the peptide for ocular delivery (POD) that can be conjugated with ophthalmic drugs (targets) to improve delivery of those targets to the eye. -To date POD has been shown to help all types of compounds (e.g. small molecules, proteins, and DNA) penetrate the ocular tissue more effectively than the standalone compound -Creation of a patentable new molecular entity -Commercial prospects and clinical/regulatory feasibility of Wet AMD indication are the most attractive. -Conjugating POD with targets will increase intercellular uptake and tissue penetration and improve efficacy. -Commencing in vivo studies in relevant animal models.