Composition, Methods and Products Comprising Human Papillomavirus for Detecting and Treating a Cancer

Applications: Detecting and treating cancer in any stage of development.

This invention comprises methods for screening patients for cancer wherein the methods detect an HPV in a biopsy from a patient. Also, disclosed are compositions and products for screening and for treating cancer in a patient, as well as methods of treating a patient afflicted with a cancer.

Claims of issued patent:

1. A method of screening a patient for breast cancer, the method comprising: a) assaying for the presence of human papillomavirus in a sample from a biopsy taken from a patient, wherein said assaying comprises amplifying human papillomavirus gene sequences by use of a pair of primers to produce an amplified product, and probing said amplified product for the presence of HPV 16 and a second human papillomavirus selected from the group consisting of HPV18, HPV31, HPV33, HPV35, HPV45, HPV58, wherein said pair of primers is SEQ ID NO: 1 and SEQ ID NO: 2, and wherein presence of HPV 16 and said second human papillomavirus is indicative of breast cancer in said patient.

2. The method of claim 1 wherein the patient is a human, wherein the cancer is in any stage of development.

3. The method of claim 1 wherein the biopsy is obtained by performing the technique of ductal lavage on a breast of a patient.

4. The method of claim 1 wherein said amplifying is achieved by use of polymerase chain reaction amplification.

5. The method of claim 1 wherein said amplifying is achieved by use of reverse-transcription polymerase chain reaction amplification.

U.S. Patent #6,884,605

Available for Exclusive Licensing

00-25 Hermonat

No known limitations

File Number: 00-25 

Web site: http://www.uams.edu/bioventures

Disease: Cancer