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Method to Alter the Receptor Effects of a Drug
University of California System: University of California, Davis - UC Davis
posted on 07/01/2009
A method to alter anesthetic drug specificity for anesthetic-sensitive channels and receptors
Suggested Uses
This invention has application to both clinical anesthetic drug development and to the development of research pharmaceuticals where specific receptor agonists/antagonists are often required.
Advantages
There is currently no known alternative for achieving N-methyl-D-aspartate (NMDA) versus gamma-aminobutyric acid (GABA) receptor specificity for a family of compounds. This invention may modify any anesthetic or candidate anesthetic receptor-acitivity profile at low-affinity sites by small structural changes.
Detailed Description
A researcher at the University of California, Davis has discovered a way to modify the receptor specificity of anesthetic drugs. This invention may create new compounds, or modify drugs, that have desirable anesthetic properties.
File Number: 19237
| Copyright: | ©2009-2010, The Regents of the University of California |
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This innovation currently is not available for online licensing. Please contact Randi Jenkins at University of California System: University of California, Davis - UC Davis for more information.
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