Innovation

Novel Nanowire Field-Effect Transistor Biosensor With Superb Sensitivity

University of California System: University of California, Los Angeles - UCLA
posted on 02/24/2012

There has been an increasing demand for highly sensitive bio- and chemical sensor devices. Optical and MEMS methods provide highly specific platforms; however, problems of scalability and cost have hindered their employability in real field applications. With the recent advancements in nanotechnology, integrated systems have been developed through the use of silicon nw-FETs. However, the low level of output signal in the design of these sensors limit their potential applications.

Suggested Uses

Chemical/Biomedical sensors

  • Toxin detection, Disease diagnosis, Drug screening, Label-free biosensing (proteins, DNA, enzymes), Environmental monitoring

Advantages

  • Standard semiconductor processing methods
  • Tunable electronic properties

Innovation Details
 

Detailed Description

Researchers at UCLA have developed a novel, highly-sensitive integrated biochemical sensor with significant detection performance. Through integrating a sensing nanowire with a nw-FET channel, a built-in signal amplification mechanism is introduced, which greatly enhances detection sensitivity. Additionally, because the technology is compatible with conventional silicon fabrication techniques, it provides a simple and low-cost solution to integrated biomedical and chemical sensors.

File Number: 22120 

Other Information:

Summary
Researchers at UCLA have developed a highly sensitive, real-time, and label-free chemical and biomedical sensor in conventional silicon nanowire Field Effect Transistors (nw-FET), utilizing a built-in signal amplification mechanism to significantly improve detection sensitivity.


IP Protection

Patent Number(s): WO2012075445
Copyright: ©2012, The Regents of the University of California

License Online

This innovation currently is not available for online licensing. Please contact UCLA Office of Intellectual Property & Industry Sponsored Research at University of California System: University of California, Los Angeles - UCLA for more information.

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February 11, 2009

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