Follow this innovation
[ via 
] [?]
Improved Voltammetric Detection In Flow Streams
University of California System: University of California, Riverside
posted on 09/13/2011
Brief description unavailable
Suggested Uses
The improved voltammetric detection offers a powerful method of detection for a wide range of electrochemical flow situations, such as is found in HPLC, fundamental electrochemical processes, and neuroanalysis.
Advantages
- Improved detection limit (by more than two orders of magnitude, down to picomolar detection in flow streams).
- Capability of discriminating a given signal from a mixture.
- Retention of thermodynamic and kinetic information.
- Increased sensitivity to the standard heterogeneous rate constant.
Detailed Description
Fast scan voltammetry has been used for electrochemical detection in numerous flow situations, such as high performance liquid chromatography (HPLC), flow injection analysis, and in vivo measurement of various electroactive neurotransmitters. While voltammetry offers improved selectivity over direct current (dc) amperometry, dc methods generally offer better signal quality and better sensitivity.
Scientists at the University of California have developed a method of voltammetric detection that surpasses the detection limit of dc amperometry by two orders of magnitude and also possesses the capability of discriminating a given signal from a mixture. Their research indicates that this detection limit can be further improved by more than an order of magnitude, making this an extremely powerful method for neuroanalysis.
File Number: 10048
| Patent Number(s): | 5650061 |
|---|---|
| Copyright: | ©2009-2010, The Regents of the University of California |
This innovation currently is not available for online licensing. Please contact Patricia Anderson Cotton at University of California System: University of California, Riverside for more information.
request more info
ProfileFind more innovations
