Innovation

ANTIBODIES TO CELL CYCLE AND TRANSCRIPTIONAL REGULATORS

University of California System: University of California, Riverside
posted on 06/21/2009

Brief description unavailable


Innovation Details
 

Detailed Description

Scientists at the University of California and the University of Wisconsin working on cell cycle and development research have created a suite of antibodies to important transcriptional regulators.  These antibodies target the following:

Histone 2B

Phosphorylated Histone 2B

TAF1 (Tata Box Binding Protein Associated Factor 1)

Ash1 (histone methyl-transferase that methylates Histones 3 and 4)

MLL (a DNA-binding protein that methylates histone H3)

MDU (Drosophila Set/MBD protein)

The following table provides more deatail:

Antigen

Species

Type

Reactivity

H2B

Drosophila

Monoclonal (rat)

universal

H2B-S33P (phospho-group on serine 33)

Drosophila

Monoclonal (rat)

Polyclonal (rabbit)

Drosophila

Ash1 (epigenetic activator) COOH term

Drosophila

Monoclonal (rat)

Polyclonal (rabbit)

Drosophila

Ash1 (epigenetic activator) COOH term

Drosophila

Polyclonal

Drosophila

TAF1 (coactivator)

Drosophila

Mono (rat) and polyclonal (rabbit)

Drosophila

MLL (mammalian epigenetic activator)

Mouse

Polyclonal (rabbit)

Mouse, Human

Mdu (Drosophila Set/MBD protein

Drosophila

Monoclonal (rat)

Drosophila

File Number: 10288 


IP Protection

Patent Number(s): 2006/0115482
Copyright: ©2009-2010, The Regents of the University of California

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This innovation currently is not available for online licensing. Please contact Michael Arciero at University of California System: University of California, Riverside for more information.

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Case Manager:

Michael Arciero Michael Arciero

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February 11, 2009

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