Cryogenic Fluid Management (CFM) Flow Cell with Internal Referencing

University of Utah Technology Commercialization Office
posted on 03/31/2011

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Intellectual Property: A non-provisional patent application (US 2010/0075860) and PCT patent application (WO 2010/034010) have been published for this technology.

Development Stage: This technology is part of an active and ongoing research program and has been demonstrated to work in proof-of-concept experiments that include a working prototype.  It is available for developmental research support and licensing under either exclusive or non-exclusive terms.

Related Research & Publications:
Dr. Gale's web page: http://www.mems.utah.edu/Student_Pages/bruce_gale.htm

Wasatch Microfluidics: http://www.microfl.com/

"Spot and hop": Internal referencing for surface plasmon resonance imaging using a three-dimentional microfluidic flow cell array" Eddings, M. A.; Eckman, J. W.; Arana, C. A.; Papalia, G. A.; Connolly, J. E.; Gale, B. K.; Myszka, D. G. Anal. Biochem. 2009, 385(2), 309-313.

See also: U-3916: "An Integrated Microfluidic Interface System for Well Plate Formats",

U-3598: "Spotting Technique for High Concentration Protein Microarrays" and U-4459: "Tip Overlay for the Continuous Flow Microspotter"

Keywords: Microfluidic, protein array, biosensor, biacore, flexchip, SPR