Method for Pathway Level Analysis

Wayne State University
posted on 01/16/2012

Method for Pathway Level Analysis

Case ID:

07-854

Description:

Sorin Draghici

Director, Intelligent Systems and Bioinformatics Laboratory

Department of Computer Science @ Wayne State University

Background:

A common hurdle in the analysis of genomics data is trying to understand the underlying processes in the context of all the complex interactions taking place on various signaling pathways. A Wayne State University researcher has developed a new method for pathway analysis. The new technique leverages statistical methodology to construct various models and identify the most relevant pathway in a given experiment.

Competitive Advantage:

· This approach calculates an impact factor (IF) for each pathway incorporating parameters

Commercial Applications:

Possible commercial uses include:

· Useful in all high throughput genomics experiments

Publication(s):

Draghici S, et al. A systems biology approach for pathway level analysis. Genome Res. 2007; 17:1537-1545.

Publication link: http://vortex.cs.wayne.edu/papers/Genome_Research_reprint1537.pdf

If you are interested in learning more about this patented technology please contact:

Andrew M. Olson

Technology Commercialization Office @ Wayne State University

(313) 874-5619