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Washington University in St. LouisThe Office of Technology Management assists members of the University community in the transfer of technology to private companies for the benefit of society while generating income to support research and education. The OTM manages a wide variety of intellectual properties arising from research programs throughout the University. The areas we address range from patents, copyrights, know-how, and proprietary materials to assisting faculty with consulting agreements and research contracts.
Our current portfolio contains active and pending patents in areas of technology ranging from gene therapies to magnetics. The research projects being conducted by University faculty, students and staff lead to an increasing number of new inventions each year. With federal agency support surpassing $400 million and a history of attracting the finest scientific minds, we are confident that the pace of invention will continue to accelerate. We hope that our work will benefit society and meet the needs of the private sector as well.



87 Innovations found


Novel p53 Vector Containing Facilitating Gene Manipulation
The invention describes a new reagent for p53 studies. The inventor has created a new p53 ORF containing novel restriction sites for cloning. The new ORF has the same amino acid sequence as the w...
Mouse Model to Screen for Distal PI3 Kinase Inhibition in the Prostate
The current invention describes a prostate specific mTOR knockout mouse generated by crossing TSC1-LoxP mice with transgenic mice expressing cre recombinase under the control of the androgen promot...
Transgenic Mouse with Prostate-Specific, Constitutively Active mTOR
The current invention describes a novel transgenic mouse in the FVB/n strain background that expresses constitutively active mTOR under the prostate-specific probasin promoter. Mice develop consti...
Improved contrast agent for MRI using fluorinated nanoparticles
Washington University is actively seeking partners to further develop an innovative new contrast agent for magnetic resonsnace imaging that could revolutionize diagnostic imaging. The agent, which...
Spatial Delayed Response (SDR) Tasks Software
The Spatial Delayed Response (SDR) Task or Oculo-motor delayed response (OMDR) task has been used extensively for assessing spatial working memory.
ABCA1 Monoclonal Antibodies
A hybridoma cell line that produces monoclonal antibodies (mAbs) against murine ABCA1 transporter protein.
p-neo-LoxP Plasmid
We are offering a cloning vector containing a pgk-neo cassette flanked by 2 LoxP sites. When used in conjunction with the cre-recombinase, the vector allows for the removal of the pgk-neo cassette.
Contrast Agent for MR Angiography with No Background Signal
“Researchers at Washington University have developed a contrast agent with a superior contrast-to-noise ratio; the agent exhibits no background tissue signal, does not depend on the conventio...
Chimeric Kidney and In Vitro Preservation Methods
This technology provides methods to grow new kidneys using renal porcine primordial tissue.
Polybayes Software
PolyBayes is a computer program for the automated analysis of single-nucleotide polymorphism (SNP) discovery in redundant DNA sequences. The primary motivation for its development is to provide a g...

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